| Acronym | Definition |
|---|
| CCLE | Creating a Collaborative Learning Environment (University of Wisconsin) |
| CCLE | Chronic Cutaneous Lupus Erythematosus |
| CCLE | Center for Cognitive Liberty & Ethics |
| CCLE | Collectif contre les Expulsions (French: Collective against Evictions; Belgium) |
| CCLE | Commission on Continuing Legal Education |
| CCLE | Christian Copyright Licensing (Europe) Ltd |
| CCLE | Centre de Coopération Linguistique et Éducative (French: Center for Linguistic and Educational Cooperation) |
| CCLE | Check Point Certified Licensing Expert (software professional) |