| Acronym | Definition |
|---|
| DFR | Département de Formation et de Recherche (French: Department of Training and Research; various locations) |
| DFR | Direction de la Formation et de la Recherche (French: Directorate of Training and Research) |
| DFR | Dryden Flight Research (US NASA) |
| DFR | Decaf French Roast (coffee) |
| DFR | Dallas Fire Rescue (Texas) |
| DFR | Dialysate Flow Rate (nephrology) |
| DFR | Dean Forest Railway (heritage railway; UK) |
| DFR | Draft Final Report |
| DFR | Dropped Frame Rate |
| DFR | Defer |
| DFR | Division of Forest Resources |
| DFR | Distal Femoral Replacement (surgery) |
| DFR | Design For Reliability |
| DFR | Dual Fluid Reactor (nuclear power) |
| DFR | Duty of Fair Representation |
| DFR | Detailed Functional Requirement (US DoD/Defense Reutilization and Marketing Service software development) |
| DFR | Dounreay Fast Reactor (fast breeder nuclear reactor) |
| DFR | Digital Fault Recorder |
| DFR | Douglas Fir Resort and Chalets (Canada) |
| DFR | Detailed Feasibility Report |
| DFR | Danmarks Forskningspolitiske Råd (Danish: Danish Council for Research Policy) |
| DFR | Dry Film Resist |
| DFR | Decreasing Failure Rate |
| DFR | Drilling Factual Report |
| DFR | Digital Family Reunion |
| DFR | Defence Force Recruiting |
| DFR | Dropped From Rolls |
| DFR | Doctor's First Report (workman's compensation) |
| DFR | Dark Force Rising |
| DFR | Divine Forces Radio |
| DFR | Defense Fuel Region (US DoD) |
| DFR | Dialysis Facility Report |
| DFR | Design For Reuse |
| DFR | Dartmouth Formula Racing (Thayer School of Engineering, Dartmouth College) |
| DFR | Diary Feedback Report (USMC) |
| DFR | Direct Fingerprint Reader |
| DFR | Delta Force Revolution (first person shooter gaming squad) |
| DFR | Dave Freitas Racing |
| DFR | Directorate of Fisheries Research (UK; now Centre for Environment, Fisheries and Aquaculture Science) |
| DFR | Double Frequency Recording |
| DFR | Decision Feedback Receiver |
| DFR | Demonstration Fast Reactor (energy industry) |
| DFR | Defensive Fumble Recovery (football) |
| DFR | Daily Field Report |
| DFR | Digital Flight Recorder |
| DFR | Durst Fetner Residential (New York, NY) |
| DFR | Disk File Read |
| DFR | Direction Finding Receiver |
| DFR | Damaged Fuel Relocation |
| DFR | Doseur Fixation Ronde (French: Round Feeder Attachment) |
| DFR | Division of Financial Regulation |
| DFR | Detail Fatigue Rating |
| DFR | Department of Fisheries Research (UK) |
| DFR | Distributed Flow Routing |
| DFR | Direct Funding Report |
| DFR | Dynamic Faulty Recovery |
| DFR | Dragonfly Ripple (band) |
| DFR | Division of Financial Responsibility |