| Acronym | Definition |
|---|
| DIO | Diode |
| DIO | Defence Infrastructure Organisation (UK) |
| DIO | Délégué à l'Information et à l'Orientation (French: Delegate for Information and Guidance) |
| DIO | Digital Input/Output |
| DIO | Distributed Input Output |
| DIO | Disk Input Output |
| DIO | Digital Input Output |
| DIO | Data Input Output |
| DIO | Device Input Output |
| DIO | Designated Institutional Official |
| DIO | Defence Intelligence Organisation (Australia) |
| DIO | Days Inventory Outstanding |
| DIO | Down in One |
| DIO | District Informatics Officer (India) |
| DIO | Data Input-Output |
| DIO | Defence Industries Organisation (Iran) |
| DIO | Dealer Installed Option (automotive) |
| DIO | Defensive Information Operations |
| DIO | Discrete Input/Output |
| DIO | Defense Intelligence Officer |
| DIO | Division Informatique de l'Observatoire (French: Computing Division of the Observatory) |
| DIO | Direct Input Output |
| DIO | Digital Information Office |
| DIO | Deiodinase, Iodothyronine |
| DIO | Director of Industry Operations (Bureau of Alcohol, Tobacco and Firearms) |
| DIO | Dépistage Individuel Organisé du Cancer (French: Screening Individuals with Cancer; software) |
| DIO | Division Information Officer |
| DIO | District Intelligence Officer |
| DIO | Dietary-Induced Obesity |
| DIO | Director of Industrial Operations |
| DIO | Directorate of Industrial Operations |
| DIO | District Irrigation Officer |
| DIO | Dave Ivaz Orchestra |
| DIO | Deferred Interest Obligation |
| DIO | Device Integration Object |
| DIO | Declaration of International Operations (US FAA) |