| Acronym | Definition |
|---|
| CSME | CARICOM Single Market and Economy |
| CSME | Caribbean Single Market and Economy |
| CSME | Canadian Society for Mechanical Engineering |
| CSME | Club Sportif Multisections d'Epinay-sur-Seine (French sports club) |
| CSME | CSIRO (Commonwealth Scientific and Industrial Research Organisation) Sustainable Materials Engineering |
| CSME | Clinically Significant Macular Edema |
| CSME | Certified Social Media Expert |
| CSME | Club Sportif Municipal d'Eaubonne (French: Eaubonne Municipal Sports Club; Eaubonne, France) |
| CSME | Center for Science and Mathematics Education (North Dakota State University) |
| CSME | Confédération Syndicale Mondiale des Enseignants (French: World Confederation of Teachers) |
| CSME | Control Site Multiplexer and Exchange |
| CSME | Certified Subject Matter Educator |