| Acronym | Definition |
|---|
| AFSC | American Friends Service Committee |
| AFSC | Air Force Sustainment Center |
| AFSC | Alaska Fisheries Science Center |
| AFSC | Air Force Specialty Code |
| AFSC | Air Force Systems Command |
| AFSC | Army Field Support Command |
| AFSC | Air Force Space Command |
| AFSC | Air Force Safety Center |
| AFSC | Agriculture Financial Services Corporation (Alberta, Canada) |
| AFSC | Armed Forces Staff College |
| AFSC | Armed Forces Services Corporation |
| AFSC | Alzheimer's Family Services Center (California) |
| AFSC | Alaska Fire Science Consortium (Joint Fire Science Program) |
| AFSC | Air Force Satellite Control |
| AFSC | African Friends Service Committee |
| AFSC | AMC Field Support Center |
| AFSC | Advanced Features Service Center (AT&T) |
| AFSC | Air Forces Services Command |
| AFSC | Allowable Foreign Selling Costs |
| AFSC | Air Force Supply Code |
| AFSC | Artillery Fire Support Center |
| AFSC | Association of Former Singing Cadets (College Station, Texas) |