COSB
| Acronym | Definition |
|---|---|
| COSB | California Oaks State Bank |
| COSB | Council of Schools for the Blind (US and Canada) |
| COSB | Chamber Orchestra of the South Bay (California) |
| COSB | Class of Service Buffer (data communications) |
| COSB | City of Oxford Silver Band (est. 1887; UK) |
| COSB | Central Operations and Systems Branch (Australia) |