| Acronym | Definition |
|---|
| CLTS | Community Led Total Sanitation |
| CLTS | Connectionless-Mode Transport Service |
| CLTS | Connectionless Transport Service |
| CLTS | Children's Long-Term Support (Wisconsin) |
| CLTS | Clear Task Switch Flag |
| CLTS | Centre Lorrain des Technologies de la Santé (French: Lorrain Center of Health Technologies; Lorraine, France) |
| CLTS | Concordia Lutheran Theological Seminary (St. Catherine's, Ontario, Canada) |
| CLTS | Canadian Livestock Tracking System (Canada) |
| CLTS | Contractor/Combined Life Time Support |
| CLTS | Community Living Temiskaming South (Haileybury, Ontario, Canada) |
| CLTS | Cis-Lunar Transportation System |