| Acronym | Definition |
|---|
| COST | Committee on Science and Technology |
| COST | Council on State Taxation |
| COST | Cooperation in the Field of Scientific and Technical Research |
| COST | Church of Spiritual Technology |
| COST | College of Saint Thomas (Fort Worth, Texas) |
| COST | Contingency Operations Support Tool (US DoD) |
| COST | Comité d'Orientation Scientifique et Technique (French: Scientific and Technical Steering Committee; various organizations) |
| COST | Cooperation in the Field of Science and Technology Research (Europe) |
| COST | Contracting Officer Support Tool |
| COST | Charlotteans Opposed to Sports Taxes (North Carolina) |
| COST | Citizens Opposed to the SunCoast Tollway, Inc. (Florida) |
| COST | Contemporary Operations Studies Team |
| COST | Council of Summer Theatres |