| Acronym | Definition |
|---|
| DESE | Department of Elementary and Secondary Education |
| DESE | Department of Elementary and Secondary Education (Jefferson City, MO) |
| DESE | Diploma de Estudos Superiores Especializados (Portuguese: Diploma of Specialized Higher Studies) |
| DESE | Division of Environmental Science and Engineering (National University of Singapore) |
| DESE | Doctorat d'Etudes Supérieures Européennes (French: European Doctorate in Higher Education) |
| DESE | Department of Secondary Education (Missouri) |
| DESE | Department of Environmental Sciences and Engineering (university department) |
| DESE | Data Encryption Standard Encryption (protocol) |
| DESE | Division of Electrical and Software Engineering (FDA) |