| Acronym | Definition |
|---|
| DIRC | Digital Imaging Research Centre |
| DIRC | Dubai International Racing Carnival (Dubai, United Arab Emirates) |
| DIRC | Defense Investigative Review Council (US DoD) |
| DIRC | Délégation Interrégionale a la Recherche Clinique (French: Delegation to the Inter-Regional Clinical Research) |
| DIRC | Disability Information & Resource Centre South Australia |
| DIRC | Disability Information & Referral Centre Eastern Sydney |
| DIRC | Democrat in Republican Clothes (politics) |
| DIRC | DOE Internal Review Committee |
| DIRC | Dragonmount Internet Relay Chat client (Dragonmount Networks) |
| DIRC | Disaster Information Resource Center (FEMA) |