| Acronym | Definition |
|---|
| DOE | Department Of Energy (US) |
| DOE | Department of Education (US) |
| DOE | Depending On Experience (jobs & classified ads) |
| DOE | Department Of Ecology |
| DOE | Diário Oficial do Estado (Portugese: Official State Gazette; Brazil) |
| DOE | Design Of Experiment |
| DOE | Department of the Environment |
| DOE | Dividends on Equity |
| DOE | Director of Environment (various locations) |
| DOE | Dyspnea On Exertion |
| DOE | Department of Expenditure (India) |
| DOE | Diario Oficial de Extremadura (Extremadura, Spain) |
| DOE | Director of Education |
| DOE | Double Open End (filters) |
| DOE | Director of Engineering |
| DOE | Dossier des Ouvrages Exécutés (French: Record of Works Executed; building construction) |
| DOE | Depends On Experience |
| DOE | Dank of England |
| DOE | Distributed Object Environment |
| DOE | Determination of Eligibility |
| DOE | Date of Entry |
| DOE | Design of Experiments |
| DOE | Database Object Editor |
| DOE | Dynamic Operating Environment |
| DOE | Designated Operational Entity |
| DOE | Department of Electronics |
| DOE | Date of Execution |
| DOE | Danube-Oder-Elbe (water corridor) |
| DOE | Diffractive Optical Elements |
| DOE | Dictionary of Old English |
| DOE | Date of Enrollment |
| DOE | Dependant on Experience (UK) |
| DOE | Date Of Enlistment (USAF) |
| DOE | Date of Effect |
| DOE | Denominación Oficial Española (Spanish: Spanish Official Designation; pharmacology) |
| DOE | Direct Order Entry |
| DOE | Department of Extension |
| DOE | Department of Enforcement (securities) |
| DOE | Date Of Entitlement |
| DOE | Depth of Exploration |
| DOE | Dragons of Eisengard (gaming guild) |
| DOE | Direct Operating Expense (financial management) |
| DOE | Diabetes Outpatient Education (Rhode Island) |
| DOE | Departmental Operating Expense |
| DOE | Duke of Edinburgh |
| DOE | Diocese of El Obeid |
| DOE | Design of Experiences |
| DOE | Due-Out Exists |
| DOE | Difficulty On Exertion |
| DOE | Data Origin Level – Toll Equipment Input |
| DOE | Dedicated Outbound Extension (Sprint) |
| DOE | Disributed Object Everywhere |