| Acronym | Definition |
|---|
| DSME | Diabetes Self Management Education |
| DSME | Daewoo Shipbuilding & Marine Engineering Co., Ltd. |
| DSME | Division of Science and Mathematics Education (Michigan State University) |
| DSME | Department of Science and Mathematics Education |
| DSME | Dimensionnement des Structures Mécaniques dans Leur Environnement (French: Design of Mechanical Structures in Their Environment) |
| DSME | Digital Systems Middle East |
| DSME | Devenus Sourds et Mal Entendants (French: Deaf and Hard of Hearing) |
| DSME | Domain-Specific Modeling Environment |
| DSME | Division of Studies in Medical Education |
| DSME | Dark Slayer Mutation Engine (polymorphic virus) |
| DSME | Diabetic Self-Management Education |
| DSME | Device State Management Entity |
| DSME | Directory Services Management Exit |
| DSME | Department of Studies in Medical Education (University of Alberta; Canada) |
| DSME | Director of Student Medical Education |
| DSME | Domain-Specific MIPS Environments |
| DSME | Durban Society Model Engineers (South Africa) |
| DSME | Defence Submarine Engineering |
| DSME | Distinguished Sales and Marketing Executives (award) |
| DSME | Damn Smart Mail Enterprise |
| DSME | Drewsif Stalin's Musical Endeavors (band) |
| DSME | Division for Stewardship and Mission Education |
| DSME | Dual Shape Memory Effect (metals) |
| DSME | Diabetes Self Monitoring Education |
| DSME | Department for Surface Mining and Enforcement |