| Acronym | Definition |
|---|
| ECSC | Expedia CruiseShipCenters (Mandeville, LA) |
| ECSC | East Coast Surfing Championship (Virginia Beach; Virginia) |
| ECSC | European Economic and Social Committee (EU) |
| ECSC | Environmental Cooperative Science Center (Florida) |
| ECSC | European Committee for Social Cohesion |
| ECSC | Emerald Coast Science Center (Fort Walton Beach, FL) |
| ECSC | European Coal & Steel Community |
| ECSC | European Conference on Satellite Communications |
| ECSC | Étoile Cycliste Saint Clairoise (French cycling club) |
| ECSC | European Chess Solving Championship |
| ECSC | Electric Cooperatives of South Carolina, Inc. |
| ECSC | European Customer Support Center |
| ECSC | Ector County Senior Center |
| ECSC | Environmental Control System Controller |
| ECSC | Ethical Culture School Camp (former children's camp, Cooperstown, New York) |