| Acronym | Definition |
|---|
| ESU | Emporia State University (Emporia, Kansas) |
| ESU | East Stroudsberg University (East Stroudsburg, PA, USA) |
| ESU | English Speaking Union (London, UK) |
| ESU | Electrosurgical Unit |
| ESU | Eames Storage Unit (furniture) |
| ESU | Educational Service Unit (Nebraska) |
| ESU | Emergency Services Unit |
| ESU | English-Speaking Union of the United States |
| ESU | Explorer Scout Unit (various locations) |
| ESU | Electronic Sound File |
| ESU | Entitled Software Updates |
| ESU | Electro Static Unit |
| ESU | Evolutionary Significant Unit |
| ESU | Electronic Software Update |
| ESU | Electrical System Upgrade |
| ESU | Electronic Support Unit |
| ESU | Electro-Static Unit |
| ESU | European Size Units (UK farming) |
| ESU | Elevator Support Unit (US Navy) |
| ESU | Ethernet Switch Unit |
| ESU | Environnements Sécurisés des Utilisateurs (French software) |
| ESU | Entente Sportive Usseloise (French sports club) |
| ESU | Enterprise Support Unit |
| ESU | Equal Support Unit (UK) |
| ESU | Equivalent Stormwater Unit |
| ESU | Equipment Set Up (television studio scheduling) |
| ESU | Employer Service Unit |
| ESU | Elite Strike Unit (gaming clan) |
| ESU | Electronic Sequencing Unit (starts CH-47D helicopter APU) |
| ESU | Expeditionary Surgical Unit |
| ESU | Element Supervisor Unit |
| ESU | Electronics Systems Support Unit (US Coast Guard) |
| ESU | Entertainment Switching Unit |
| ESU | Energy Studies Unit |
| ESU | Electronic Suppression Unit |
| ESU | Equivalent Spousal Unit |
| ESU | Effective Single-User |
| ESU | Environmental Simulator Unit |