| Acronym | Definition |
|---|
| DOTS | Department of Technology Services (various organizations) |
| DOTS | Directly Observed Treatment Short-Course |
| DOTS | Directly Observed Treatment Strategy |
| DOTS | Difference of Two Squares (mathematics) |
| DOTS | Dozens of Terrific Stamps |
| DOTS | Database of Transcribed Sequences |
| DOTS | Document Tracking System |
| DOTS | Day of the Sword (band) |
| DOTS | Dose-Responsiveness, Time-Course, Susceptibility Factors (used in classifying adverse drug reactions) |
| DOTS | Dynamic Ocean Tracking System (US FAA) |
| DOTS | Digital-Optical Technology System |
| DOTS | Department of Trade Statistics |
| DOTS | Directly Observed Treatment/Therapy Short Course |
| DOTS | Deformities Open wounds Tenderness Swelling |
| DOTS | Director Of Training and Simulations |
| DOTS | Directory Order Transmission System |
| DOTS | Dredging Operations Technical Services |