| Acronym | Definition |
|---|
| ESL | English as a Second Language |
| ESL | Electronic Sports League |
| ESL | Electronic System Level |
| ESL | Energy Systems Laboratory |
| ESL | Elementary School Level (various locations) |
| ESL | Environmental Solutions Ltd. (various locations) |
| ESL | English Sign Language |
| ESL | End of Service Life (product lifetime) |
| ESL | Ejercito Sirio Libre (Spanish: Free Syrian Army) |
| ESL | Early School Leaving |
| ESL | European Super League (sports) |
| ESL | Environmental Sciences Laboratory (various locations) |
| ESL | Extended Shelf Life |
| ESL | Electrostatic Loudspeaker |
| ESL | Enterprise Systems Library |
| ESL | Ethernet Service Layer |
| ESL | Enterprise Storage Library |
| ESL | Extensible Style Language |
| ESL | Electronic Service Literature |
| ESL | Engineering Systems Laboratory (various schools) |
| ESL | Eighteenth Street Lounge (record label) |
| ESL | Enghouse Systems Limited (Ontario, Canada) |
| ESL | Electronic Services, Ltd. (various locations) |
| ESL | Equivalent Series Inductance (L is inductance) |
| ESL | Elista (Russia) |
| ESL | Étoile Saint Laurent (French sports club) |
| ESL | Entente Sud Lyonnais (French athletic club) |
| ESL | Electronic Shelf Label |
| ESL | Employer Stop Loss (insurance) |
| ESL | Exit Stage Left (Rush album) |
| ESL | East Slavic (linguistics) |
| ESL | Equivalent Series Inductance (electronic component leads) |
| ESL | Executive Search, Ltd. |
| ESL | Electron-Stimulated Luminescence (lighting technology) |
| ESL | Ecological Studies on the Lepidoptera |
| ESL | Electrochemical and Solid-State Letters (electronic journal) |
| ESL | Electronic Systems Laboratory |
| ESL | Ether-Serial Link (computer device) |
| ESL | Embedded Systems Laboratory |
| ESL | Eastman Savings and Loan (Bank in Rochester, NY) |
| ESL | Études Structures Logiciels (French: Academic Software Structures) |
| ESL | Electrostatic Levitator (NASA Marshall Space Flight Center) |
| ESL | Electronic Software Licensing |
| ESL | Eastern Shores Library (Wisconsin) |
| ESL | Espace Sports et Loisirs (French: Area Sports and Leisure) |
| ESL | Expected Service Life |
| ESL | École de Surf du Léon (French surfing school) |
| ESL | etch-stop layer |
| ESL | Economic Service Life |
| ESL | Earned Sick Leave (employment-human resources) |
| ESL | Explorer Scout Leader |
| ESL | Event Specification Language |
| ESL | Énergies Services Lannemezan (French energy provider) |
| ESL | Entente Sportive Laneuvevilloise (French sports club) |
| ESL | Emergency Service Level (FAA) |
| ESL | European Sales List |
| ESL | Enterprise Software Licensing |
| ESL | End-User Subscription Licensing |
| ESL | Equivalent Single-Layer |
| ESL | Eng S Lustig Consulting Engineers Ltd (Tel-Aviv, Israel) |
| ESL | Engine Speed Limit |
| ESL | Ecological Screening Level |
| ESL | Errored Second-Line |
| ESL | Emergency Staffing Level |
| ESL | East Side LAN (Phoenix/Mesa/Chandler Arizona LAN Organization) |
| ESL | Equipment and Supply List |
| ESL | Electro Signal Labs (GE Security) |
| ESL | Engine Speed Limiting (system) |
| ESL | External Sensor Lab (US DoD) |
| ESL | Emitter Signal Library |
| ESL | Enviroplan Services Limited |