| Acronym | Definition |
|---|
| FLAME | Flexible Api for Module Based Environments |
| FLAME | Facts and Logic About the Middle East (non-profit pro-Israeli organization) |
| FLAME | Flexible API (Application Programming Interface) for Module-Based Environments |
| FLAME | Fédération pour les Agences Locales de Maîtrise de l'Energie (French: Federation of Local Agencies for Energy Conservation) |
| FLAME | Flexible Local Approximation Methods |
| FLAME | Field Level Asset Management Environment |
| FLAME | Family Life And Maternity Education |
| FLAME | Foreign Language Association for Managers in Education |
| FLAME | Fostering Learning Abilities in Marion Education (Ocala, Florida) |
| FLAME | Florida Lawyers Association for the Maintenance of Excellence, Inc. |