| Acronym | Definition |
|---|
| HEF | Higher Education Funding (various locations) |
| HEF | Hood Exhaust Fan |
| HEF | High Efficiency |
| HEF | Human Energy Field |
| HEF | Home Education Foundation |
| HEF | Himmerlands Elforsyning (Danish: Himmerlands Electricity Supply; Himmerland, Denmark) |
| HEF | High-Energy Fuel |
| HEF | High Elf (Everquest) |
| HEF | Housing Endowment Fund (Canada) |
| HEF | High-Efficiency DSN (Deep Space Network) Station |
| HEF | Hispana Esperanto-Asocio |
| HEF | High Efficiency Filter |
| HEF | Hamster Embryo Fibroblast |
| HEF | Hazardous Equipment or Facilities |
| HEF | Houston Environmental Foresight |
| HEF | Heredes Eius Fecerunt (Latin: His/Her Heirs Built, epigraphy) |