| Acronym | Definition |
|---|
| EFS | Établissement Français du Sang (French: French Blood Establishment) |
| EFS | Enfield Federal Savings (Enfield, CT) |
| EFS | Education for Sustainability (various locations) |
| EFS | Event Free Survival (survival rates in clinical trials) |
| EFS | Encrypted File System (Microsoft Windows 2000) |
| EFS | Éléments Français au Sénégal (French: French Elements in Senegal) |
| EFS | Energy for Sustainability (University of Coimbra initiative; Portugal) |
| EFS | Electronic Filing System |
| EFS | Encrypted File Sharing (computing) |
| EFS | Evangeliska Fosterlandsstiftelsen (Sweden) |
| EFS | Energy Financial Services (General Electric) |
| EFS | Euro Finanz Service (Austrian financial service) |
| EFS | Economics and Finance Society (various schools) |
| EFS | Error Free Signal |
| EFS | Enhanced Filing System |
| EFS | Enterprise File Services |
| EFS | Etherfast |
| EFS | Encrypting File System |
| EFS | Extended File System |
| EFS | Error Free Seconds |
| EFS | Electronic Financial Services (various companies) |
| EFS | École Française de Spéléologie (French: French School of Speleology) |
| EFS | Expeditionary Fighter Squadron |
| EFS | Encryption File System (Intel) |
| EFS | Energy Finance Solutions (various locations) |
| EFS | Economic and Financial Studies (various locations) |
| EFS | European Federation of Sexology |
| EFS | Electronic Filing Service |
| EFS | Embedded File System |
| EFS | Error Free Seconds (percentage) |
| EFS | Express Financial Services (various organizations) |
| EFS | Eesti Filmi Sihtasutuse (Estonian: Estonian Film Foundation) |
| EFS | Enterprise File Services (HP) |
| EFS | Email Forwarding Service (software) |
| EFS | Employment & Family Services (Cuyahoga County, OH) |
| EFS | English for Foreign Students |
| EFS | Electric Field Stimulation |
| EFS | Electric Field Strength |
| EFS | Emperor of the Fading Suns (computer game) |
| EFS | Enchanted Forest Sanctuary (Florida) |
| EFS | Enemy-Free Space (insects) |
| EFS | Enterprise Freight Shopping (software) |
| EFS | Extra Fine Structure (metallurgy) |
| EFS | Environment Friends Society |
| EFS | Enterprise File System (Kitchener, Ontario, Canada) |
| EFS | Economic Farm Surplus (farming productivity) |
| EFS | Excellent Foreign Student (various locations) |
| EFS | Ensemble Forecast System |
| EFS | Engineering Functional Specification |
| EFS | Engineering Feasibility Study |
| EFS | Enhanced Flight Screening |
| EFS | External File System |
| EFS | Export Facilitation Scheme (Australian government) |
| EFS | Environmental Friendly Solutions (UK) |
| EFS | End of Frame Sequence |
| EFS | Extreme Fantasy Sports |
| EFS | Elite Fitness System |
| EFS | Extendibility, Flexibility, Scalability |
| EFS | Escape From Samsara |
| EFS | Electronic Form System |
| EFS | Enhanced Fujita Scale (tornado strength) |
| EFS | Effective Field Size |
| EFS | Electric Funstuff (band & software company) |
| EFS | Emergency Feedwater System |
| EFS | Edwards, Faust, & Smith (Maine accounting firm) |
| EFS | Enterprise File Sharing |
| EFS | Electronic Firing Switch |
| EFS | Environmental Feasibility Study |
| EFS | Electronic Filing Systems, Inc. |
| EFS | Emergency Feeding Service |
| EFS | Elastomeric Firestop (construction) |
| EFS | Earth-Fixed System |
| EFS | Enterprise Fax Solution |
| EFS | Electric Field-induced Spectra |
| EFS | Extended Fuel System |
| EFS | Encrypting Firewall System |
| EFS | Extended Function Set |
| EFS | Exercise for the Student |
| EFS | External Focus Subassembly |
| EFS | Equal Frequency Separation |
| EFS | Electrical Feeder System |
| EFS | Essential Fire Support |
| EFS | Expert Finding Systems |