| Acronym | Definition |
|---|
| GPE | Gross-Pitaevskii Equation (physics) |
| GPE | General Protection Error |
| GPE | Government Wide Point of Entry |
| GPE | Graphic Parallelization Environment |
| GPE | Group Policy Editor |
| GPE | General Purpose Event |
| GPE | Governmentwide Point of Entry |
| GPE | Gravitational Potential Energy |
| GPE | Group Policy Editor (Microsoft) |
| GPE | Greatest Potential for Exposure (Canada) |
| GPE | Grove Park Elementary (North Carolina) |
| GPE | General-Purpose Event (ACPI) |
| GPE | Great Plains Energy Incorporated (Kansas City, MO) |
| GPE | Gold Plated Everything |
| GPE | Germ Plasm Evaluation (livestock) |
| GPE | Global Pharmacovigilance and Epidemiology |
| GPE | Green Power Experience (New York) |
| GPE | Greatest Possible Error |
| GPE | Gas Phase Epitaxy |
| GPE | General Purpose Evaporator |
| GPE | Graphite Paste Electrode |
| GPE | Galena Peak Enterprises (mining; Las Vegas, NV) |
| GPE | Gross Profit Estimate |
| GPE | Generalized Potential Energy (mechanics) |