| Acronym | Definition |
|---|
| HFS | Home for Sale |
| HFS | High-Frequency Stimulation (medical treatment) |
| HFS | Hierarchical File System |
| HFS | Held for Sale |
| HFS | Health and Family Services |
| HFS | Health Fitness Specialist (various organizations) |
| HFS | Housing and Food Services (various schools) |
| HFS | Head of Financial Services (various organizations) |
| HFS | Healthcare Financial Services (various companies) |
| HFS | Hedge Fund Strategy |
| HFS | High Level File System |
| HFS | Hybrid File System |
| HFS | Hardware Functionality Scan |
| HFS | Http File Server |
| HFS | Hurricane File System |
| HFS | Hybrid Fuel Systems |
| HFS | High Performance File System |
| HFS | Health Facilities Scotland (National Health Service; UK) |
| HFS | Hemifacial Spasm |
| HFS | Harder Faster Stronger |
| HFS | Health Food Store |
| HFS | House Financial Services (US Congress) |
| HFS | Hungry for Success (various locations) |
| HFS | Harland Financial Solutions (Lake Mary, FL) |
| HFS | Human Factors Society |
| HFS | Healthcare Financial Solutions (various companies) |
| HFS | Hospitality and Food Service (various locations) |
| HFS | Hot Finished Seamless (European Pipe Standards) |
| HFS | Hartford Food System (Hartford, CT) |
| HFS | Hartree-Fock Slater (Calculations for Arbitrary Temperature and Matter Density) |
| HFS | Hydrogen Forward Scattering |
| HFS | Hex Flange Screw (screw type) |
| HFS | High Fantasy Society |
| HFS | Helicopter Flying School (various locations) |
| HFS | Housing Finance System |
| HFS | Hope Flowers School (Bethlehem, Palestine) |
| HFS | Hallmark Financial Services (Ft. Worth, TX) |
| HFS | High Fidelity Simulator |
| HFS | Hrvatska Udruga Filmskih Snimatelja (Croation Cinematographers Society) |
| HFS | Heritage Family Study |
| HFS | Australian Department of Health and Family Services |
| HFS | Hosted Free Sites |
| HFS | Hospital Formulary System |
| HFS | Healthcare Facilitation Services |
| HFS | Hot Fuel Storage |
| HFS | Higher Frequency Subband |