| Acronym | Definition |
|---|
| GI | Government Issue (as in GI Joe) |
| GI | Get(s) It |
| GI | General Information |
| GI | Gibraltar |
| GI | Gastrointestinal |
| GI | Geophysical Institute |
| GI | Geographical Indications |
| GI | Gießen (Germany; auto license number plate) |
| GI | Glycemic Index |
| GI | Grand Island (Nebraska) |
| GI | Game Informer (video game magazine) |
| GI | Google It |
| GI | Global Illumination (graphic art) |
| GI | Gilligan's Island (TV show) |
| GI | Government Issued (gaming clan) |
| GI | Gateway Integration |
| GI | Gauge-Invariant |
| GI | Goethe-Institut |
| GI | Geospatial Information |
| GI | Gas Industry |
| GI | Global Initiative |
| GI | Gender Imbalance |
| GI | Glycemic Impact (diet) |
| GI | Geospatial Intelligence (National System for Geospatial Intelligence) |
| GI | General Investigation |
| GI | General Issue |
| GI | Gasherbrum I (26,470 ft. mountain near Pakistan-China) |
| GI | Gender Incongruence |
| GI | General Instruction |
| GI | Global Investigations (various companies) |
| GI | General Intelligence |
| GI | Galvanized Iron |
| GI | Granuloma Inguinale (aka: Donovanosis) |
| GI | Global Infrastructure |
| GI | Granulomatous Inflammation (chronic inflammation) |
| GI | Global Industries |
| GI | Garuda Indonesia (airline) |
| GI | General Inspection |
| GI | General Increase |
| GI | Graded-Index |
| GI | Greenpeace International |
| GI | Grey Iron |
| GI | G Protein, Alpha-Inhibiting |
| GI | General Illumination (pinball machine lights) |
| GI | Guard Impact (video game) |
| GI | Green Index |
| GI | Guest Investigator |
| GI | Guitar Institute |
| GI | General Infantry (less common) |
| GI | General Infantry |
| GI | Gunnery Instructor (various armed forces) |
| GI | Glossopharyngeal Insufflation (physiology) |
| GI | Guaranteed Insurability (insurance) |
| GI | Geninfo Identifier |
| GI | Global Internet Symposium |
| GI | Gesellschaft für Informatik eV |
| GI | Gas Injector |
| GI | Guest Informant |
| GI | Global Imager |
| GI | General Instruments Corporation |
| GI | Geographically Impossible |
| GI | Genuine Ilocano (Filipino from Ilocos Province) |
| GI | Global Indexing System |
| GI | General Inductee |
| GI | Global Instruments, Inc. |
| GI | Gegenschein Imager |
| GI | Gelbray International |