| Acronym | Definition |
|---|
| HEL | Helicopter |
| HEL | Home Equity Loan |
| HEL | High-Energy Laser |
| HEL | Helaman (Book of Mormon) |
| HEL | High Energy Laser |
| HEL | Hen Egg Lysozyme |
| HEL | Highly Erodible Land (USDA and National Resources and Conservation Service) |
| HEL | Header Extension Length (ATMF) |
| HEL | Hutchison Essar Ltd. (now Vodafone Essar; India) |
| HEL | Het Echte Leven (Dutch: In Real Life) |
| HEL | Hardware Emulation Layer |
| HEL | Miasto Hel (Poland) |
| HEL | Harvard Education Letter (newsletter) |
| HEL | Human Engineering Laboratory (US Army) |
| HEL | Helsinki, Finland - Helsinki (Airport Code) |
| HEL | Human Engineering Lab (Aberdeen Proving Ground, MD) |
| HEL | Hells Elite Legions (gaming) |
| HEL | Human Embryonic Lung Cell (biology) |
| HEL | High Energy Laboratory |
| HEL | Highest-Expected Loss |
| HEL | Homogeneous Enhancing Lesion |