| Acronym | Definition |
|---|
| GWR | Great Western Railway (UK Company) |
| GWR | Guinness World Records |
| GWR | Ground-Water Recharge (geology; various locations) |
| GWR | Guided Wave Radar (various companies) |
| GWR | Gloucestershire Warwickshire Railway (UK) |
| GWR | Geographically Weighted Regression |
| GWR | God's Wonderful Railway (Great Western Railway nickname) |
| GWR | Great Way Round (Great Western Railway nickname) |
| GWR | Greater Washington Region (Virginia, Maryland, and Washington, DC) |
| GWR | Gross Weight on Rail (transportation) |
| GWR | Gift with Reservation (taxation) |
| GWR | Great Western Radio (international radio group) |
| GWR | General War Reserves |
| GWR | Graphical Wireless Reporting |