| Acronym | Definition |
|---|
| HOB | House of Blues |
| HOB | Hoboken (catalogue of Haydn's works) |
| HOB | House Office Building |
| HOB | Hierarchical Object Binary |
| HOB | Head Office Building (various locations) |
| HOB | House of Bishops |
| HOB | Hang on Back (aquarium equipment, such as a filter or refugium) |
| HOB | Head of Bed |
| HOB | Hair on Broadway (salon; UK) |
| HOB | Hoboken, New Jersey |
| HOB | Height Of Burst |
| HOB | Hand-Off Block (Intel) |
| HOB | Heritage Oaks Bank (California) |
| HOB | Hosted OSS/BSS (Operations Support System/Business Support System) |
| HOB | House of Billiards |
| HOB | Hobbs, NM, USA - Lea County (Airport Code) |
| HOB | Heart of Business |
| HOB | High-Order Byte |
| HOB | High-Order Bit |
| HOB | Horst Brandstätter (software firm founder; Germany) |
| HOB | Hoes Over Bros |
| HOB | High Overbased (overbased polyalkenyl sulfonates) |