| Acronym | Definition |
|---|
| HIE | Health Information Exchange |
| HIE | Highlands and Islands Enterprise (Scotland) |
| HIE | Holiday Inn Express |
| HIE | Hypoxic Ischemic Encephalopathy |
| HIE | Health Insurance Experiment |
| HIE | High Speed Infrared (Film, Kodak) |
| HIE | Hyperimmunoglobulin E-Recurrent Infection |
| HIE | Hipertensión Inducida por el Embarazo (Spanish: Pregnancy-Induced Hypertension) |
| HIE | Health Informatics Europe (journal) |
| HIE | Health Insurance Enrollment |
| HIE | Health Insurance Exception |
| HIE | Al-Hassan Industrial Estate |
| HIE | Elliptical Metal Halide (lighting) |
| HIE | Hazard Identification and Evaluation (more commonly abbreviated HI&E) |
| HIE | Horney Industrial Electronics (Bridgeville, DE) |
| HIE | Host Interface Equipment |