| Acronym | Definition |
|---|
| GRS | Global Response Staff (US CIA) |
| GRS | Graduate School (universities) |
| GRS | Gemeentelijk Ruimtelijk Structuurplan (Dutch: Municipal Spatial Structure; Belgium) |
| GRS | Grand Rapids Symphony (Michigan) |
| GRS | Gender Reassignment Surgery |
| GRS | Generic Record Syntax |
| GRS | Global Resource Serialization |
| GRS | Global Roaming Server |
| GRS | Guided Roller System |
| GRS | General Resource Selector |
| GRS | Global Registry Services |
| GRS | Global Registry System |
| GRS | Grass Valley (Amtrak station code; Grass Valley, CA) |
| GRS | Great Red Spot (feature of Jupiter) |
| GRS | Galaxy Redshift Survey (astronomy) |
| GRS | Gamma Ray Spectrometer |
| GRS | Geodetic Reference System (datum) |
| GRS | Graduate Research Symposium (various schools) |
| GRS | General Records Schedules |
| GRS | Geoscience and Remote Sensing (Symposium) |
| GRS | Gulf Region South (US Army Corps of Engineers) |
| GRS | Ghost Research Society |
| GRS | General Railway Signal (now part of ALSTOM Transport; railway signaling equipment supplier) |
| GRS | Graduation Rate Survey |
| GRS | Geosynthetic-Reinforced Soil |
| GRS | Gesellschaft für Anlagen- und Reaktorsicherheit mbH (German: Society for Reactor Safety) |
| GRS | Global Resource Serialization (IBM) |
| GRS | Great River School (St. Paul, MN) |
| GRS | Gamma Ray Source |
| GRS | Group Reset |
| GRS | General Reconnaissance School |
| GRS | German Railway Society (est. 1981; UK) |
| GRS | General Revenue Sharing |
| GRS | Government Records Section (Society of American Archivists) |
| GRS | Galvanized Rigid Steel |
| GRS | Groundwater Replenishment System (Fountain Valley, CA) |
| GRS | Graves Registration Service |
| GRS | Global Reference System |
| GRS | Governance Reform Secretariat (Sierra Leone) |
| GRS | Grasslands Research Station (various locations) |
| GRS | Generale de Rehabilitation Services |
| GRS | Graduate Recruitment Scheme (various locations) |
| GRS | Genital Reconstruction Surgery |
| GRS | Grain Shape |
| GRS | Government Relations Services (independent consulting firm) |
| GRS | Gamma Rho Sigma (fraternity) |
| GRS | Guaranteed Rental Scheme (various locations) |
| GRS | Guilford Rail System |
| GRS | German Radar Symposium |
| GRS | Generalized Reed-Solomon (coding scheme) |
| GRS | Groupe Révolution Socialiste (French: Socialist Revolution Group, Martinique) |
| GRS | Gas Reservoir Suspension (automotive) |
| GRS | Geriatrics Review Syllabus |
| GRS | Gunner Restraint System (military vehicles) |
| GRS | Global Reservation Service |
| GRS | Global Repair Service |
| GRS | Global Reservation System |
| GRS | Faculty of Global and Regional Studies (Doshisha University; Japan) |
| GRS | Global Reconnaissance-Strike (USAF doctrine) |
| GRS | Golabi-Rosen Syndrome |
| GRS | Gainesville Rose Society (Florida, USA) |
| GRS | Gaseous Radwaste System |
| GRS | Generic Recording System |
| GRS | Greedy Routing Scheme |
| GRS | Geometric Radiating Surface |
| GRS | Gamma Remote Sensing Spectrometer |
| GRS | Global Resolution Service |