| Acronym | Definition |
|---|
| HD | High Definition |
| HD | Hard Drive |
| HD | Harley-Davidson |
| HD | Heavy Duty |
| HD | High Density |
| HD | Human Developement (course of study) |
| HD | Hard Disk |
| HD | Home Depot, Inc. (NYSE symbol) |
| HD | Head |
| HD | Hybrid Digital (radio technology) |
| HD | Hold |
| HD | Hyundai |
| HD | Honda |
| HD | Happy Days (TV show) |
| HD | Henry Draper (star catalog) |
| HD | Hilary Duff |
| HD | Hundred |
| HD | Huntington's Disease |
| HD | Hot Dog |
| HD | Heidelberg |
| HD | Home Decor |
| HD | Help Desk |
| HD | Home Defense |
| HD | Heart Disease |
| HD | Home Delivery |
| HD | Harmonic Distortion |
| HD | Högsta Domstolen (Swedish supreme court of justice) |
| HD | Higher Diploma |
| HD | Half Day |
| HD | Half-Duplex |
| HD | Historic District |
| HD | Hairdresser |
| HD | Hot Date (The Sims expansion pack) |
| HD | Huddersfield (postcode, United Kingdom) |
| HD | High Distortion |
| HD | Homeland Defense |
| HD | Hemodialysis |
| HD | Hazardous Drug |
| HD | Hodgkin's Disease |
| HD | Helper-Dependent (genes) |
| HD | Hip Dysplasia |
| HD | Hydrodynamic |
| HD | Mustard Gas |
| HD | Hemorrhagic Disease |
| HD | Helsingborgs Dagblad (Swedish newspaper) |
| HD | High Dive |
| HD | Hit Dice (role-playing games) |
| HD | Hall Director |
| HD | Health Division |
| HD | Hand Dryer (building services) |
| HD | Honorary Degree |
| HD | Hemodynamically (stable) |
| HD | Honorable Discharge |
| HD | Highway Department |
| HD | Hoe Down (party) |
| HD | High Distinction (grade) |
| HD | Hyperactive Disorder |
| HD | Housing Department |
| HD | Horizontal Distance |
| HD | High Dispersion |
| HD | Hazel Dell ( town in SW Washington) |
| HD | Human Dimension |
| HD | Helm's Deep (JRR Tolkien's The Two Towers) |
| HD | Heaven's Disciples (Christian urban music) |
| HD | House Document (USACE) |
| HD | Humanitarian Demining (US Government unexploded ordnance mission areas) |
| HD | Hüsker Dü (band) |
| HD | Heat Detector |
| HD | Homeopathic Doctor |
| HD | Hydatid Disease |
| HD | Hot Desk |
| HD | Harbor Defense |
| HD | Highly Dispersed |
| HD | High-Drag |
| HD | Heavy Drop |
| HD | Hidden Desire |
| HD | Hip-Disarticulation (amputation) |
| HD | Hurricane Days |
| HD | Harmonization Document |
| HD | Hexanedione |
| HD | Heavy Defense (gaming) |
| HD | Hardware Disease (traumatic reticulopericarditis caused by foreign bodies in cattle) |
| HD | Hrvatski Dragovoljac (Croatian: Volunteer; Zagreb football club) |
| HD | Helicopter Director |
| HD | Humidity Detector |
| HD | Hepatosis Dietetica |
| HD | Heloma Durum |
| HD | Heavy Decoy |
| HD | Horizontal Decelerator |
| HD | Household Drivers |
| HD | Half Sized Diazo Non-Reproducible Drawing |
| HD | Hydraulic Fluid, Diving |