| Acronym | Definition |
|---|
| GFC | Global Financial Crisis |
| GFC | GMD (Ground-Based Midcourse Defense) Fire Control |
| GFC | Geelong Football Club (Australia) |
| GFC | Georgia Forestry Commission |
| GFC | Grace Fellowship Church |
| GFC | Global Forest Coalition (est. 2000) |
| GFC | Gaelic Football Club |
| GFC | Generic Flow Control |
| GFC | Greek Film Center |
| GFC | Group of Friends of the Chair (World Summit on the Information Society) |
| GFC | Going For Coffee :-) |
| GFC | Gas Filter Correlation |
| GFC | Gel Filtration Chromatography |
| GFC | Glass-Fiber Composite |
| GFC | Ground Forces Command |
| GFC | Gigabit Fibre Channel (computing) |
| GFC | Grands Films Classiques (French: Great Movies Classics) |
| GFC | Gestion Financière et Comptable (French: Financial Management and Accounting) |
| GFC | Gracie Fighting Championships (mixed martial arts) |
| GFC | Georgia Family Council |
| GFC | Gillingham Football Club (UK) |
| GFC | Gay Fathers Coalition (various locations) |
| GFC | Great Firewall of China |
| GFC | Good for Construction |
| GFC | Gun Fire Control |
| GFC | Gaining Force Command |
| GFC | Gay Football Club |
| GFC | Grumman-Flexible Corporation (bus manufacturer) |
| GFC | General Facilities Card (Newbridge) |
| GFC | Global Foncard (Sprint) |
| GFC | General Functional Code |
| GFC | Gladwyne Fire Company (Gladwyne, PA) |
| GFC | Groupement Française de Coordination pour le développement des essais de performance des combustibles, lubrifiants et autres fluides utilisées dans les transports |
| GFC | God, Family & Country LLC (Davenport, IA) |
| GFC | Garibaldi Football Club (France) |
| GFC | Grand Falls Central Railway Company, Ltd |
| GFC | Graphite Fiber Composite |
| GFC | General Fabrication Contractor |
| GFC | Guidance and Flight Control (aeronautics) |
| GFC | Granulite Facies Complexes (geology) |
| GFC | Government-Furnished Concept |
| GFC | GATX (General American Transportation Corporation) Financial Corporation (Chicago, IL) |
| GFC | G Force Customs (Orange County Choppers dealership in Jackson, Michigan |