| Acronym | Definition |
|---|
| HLC | Higher Learning Commission |
| HLC | Hal Leonard Corporation (Milwaukee, WI) |
| HLC | High Light Compensation |
| HLC | Hadley Learning Community (Telford, UK) |
| HLC | Humanitarian Law Center (Kosovo) |
| HLC | High Level Controller |
| HLC | Host Language Call |
| HLC | Higher Layer Compatibility |
| HLC | High Level Committee |
| HLC | Healthcare Leadership Council |
| HLC | Home Loans Canada (CIBC Mortgages and Lending, Toronto, Ontario, Canada) |
| HLC | Hope Lutheran Church (various locations) |
| HLC | Healthy Living Center (various locations) |
| HLC | Home Loan Consultant |
| HLC | Household Life Cycle (marketing) |
| HLC | Hybrid Layer Capacitor (batteries) |
| HLC | Haugland Learning Center (Ohio) |
| HLC | High Layer Compatibility |
| HLC | High Level Control |
| HLC | Hospital Liaison Committee |
| HLC | Honolulu Liquor Commission (Honolulu, HI) |
| HLC | Heartless Crew (band, UK) |
| HLC | Housing Leadership Council |
| HLC | Housing Legal Clinic (Australia) |
| HLC | Habitual Line Crosser |
| HLC | Help Learning Center (Philippines) |
| HLC | Huntsville Lakes Council (Canada) |
| HLC | High Level Communications (Italy) |
| HLC | Historic Landscape Character(isation) (UK) |
| HLC | Half Life Chess |
| HLC | Host LAN Controller |
| HLC | Heavy/Light Corps |
| HLC | Host LAN Computer |
| HLC | Home Office II Line Card (Nortel) |
| HLC | Hard-Limited Channel |
| HLC | Historic Lotus Club (automotive group) |
| HLC | Hierarchical Caching System |
| HLC | HEED (Health, Education and Economic Development) Language Center (Bangladesh) |