| Acronym | Definition |
|---|
| HOC | Hands of Christ |
| HOC | House of Commons |
| HOC | Higher-Order Component (computer programming) |
| HOC | Heart of Camden (New Jersey) |
| HOC | Hospital Outpatient Clinic |
| HOC | Head of the Caudate (neurochemicals) |
| HOC | House of Councilors (Japan) |
| HOC | House of Correction (various locations) |
| HOC | High Oil Consumption |
| HOC | Holy Orthodox Church |
| HOC | Host Organizing Committee (various organizations) |
| HOC | Home Ownership Center |
| HOC | Hellenic Olympic Committee |
| HOC | Head of Chancery |
| HOC | Human Intelligence Operations Cell (US DoD) |
| HOC | Hospice of the Chesapeake (Laurel, MD) |
| HOC | Home Owners Club (contractor resource) |
| HOC | High Oil Corn (livestock) |
| HOC | Humanists of Colorado (Denver, CO) |
| HOC | Humanitarian Operations Center |
| HOC | House of Communication (Germany) |
| HOC | Historic Oregon City (Oregon City, OR) |
| HOC | Heroes of Cybertron (Transformers, gaming) |
| HOC | Hands-On Component |
| HOC | Hearing Officer Conference |
| HOC | Heap of Crap |
| HOC | Home of Champions (monument; British Columbia, Canada) |
| HOC | Halogenated Organic Compound |
| HOC | Helicopter Operations Coordinator |
| HOC | High Off Contact |
| HOC | History Of Coverage |
| HOC | Home Owners Cover (insurance) |
| HOC | Highest Outgoing Channel |
| HOC | Homepage of Chemometrics |
| HOC | Hazardous Organic Constituents |
| HOC | Hydrophobic Organic Chemical |
| HOC | Headquarters Operations Company (Army specific) |
| HOC | Halogenated Organic Carbon |
| HOC | Higher Order Concern (writing) |
| HOC | Hand of Conviction (gaming, EverQuest) |
| HOC | Herndon Optimist Club (Herndon, VA) |
| HOC | Head Of Component |
| HOC | Half Operational Capability |
| HOC | Hybrid Operational Control |
| HOC | House of Clairice |
| HOC | Hurricane Operations Center |