CDLE
| Acronym | Definition |
|---|---|
| CDLE | Colorado Department of Labor and Employment |
| CDLE | Customized Digital Line Equipment |
| CDLE | Child-Driven Learning Environment (education; various locations) |
| CDLE | Chronic Discoid Lupus Erythematodes (skin disease) |
| CDLE | Customs Drugs Law Enforcement (Ireland) |