| Acronym | Definition |
|---|
| GME | Graduate Medical Education |
| GME | Greater Middle East (geopolitics) |
| GME | Goods Market Equilibrium (economics) |
| GME | Global Motion Estimation |
| GME | General Motors Europe |
| GME | Gestore Mercato Elettrico (Italian: Manager Electricity Market) |
| GME | Generic Modeling Environment |
| GME | Genomes, Medicine and the Environment |
| GME | Granulomatous Meningoencephalomyelitis |
| GME | Global Motion Estimation (video coding) |
| GME | Garrison Mobile Equipment |
| GME | General Medical Examination (health assessment) |
| GME | Glen Martin Engineering |
| GME | Goddard Medium Energy |
| GME | Generalized Master Equation (quantum statistical mechanics) |
| GME | Gimbal-Mounted Electronics |
| GME | Group Managing Editor |
| GME | Global Mass Extinction |