| Acronym | Definition |
|---|
| HBO | Home Box Office (premium movie channel on USA cable systems) |
| HBO | Hyperbaric Oxygen |
| HBO | Hyperbaric Oxygenation |
| HBO | Hollywood Bowl Orchestra (California) |
| HBO | Hipparchus Binary Object |
| HBO | Home Box Office |
| HBO | halo.bungie.org |
| HBO | Hoger Beroeps Onderwijs |
| HBO | Honey Bunches of Oats (cereal) |
| HBO | Historische Bildungsforschung Online (German history of education research website) |
| HBO | Help A Brother Out |
| HBO | Healthy Birth Outcomes ( various organizations) |
| HBO | Humboldt, Nebraska (airport code) |
| HBO | Horrible Body Odor |
| HBO | Handled By Officer (police communications) |
| HBO | Hand Baggage Only |
| HBO | Hamilton Basketball Association (Recreation League in Canadian City) |
| HBO | High Band Operator |
| HBO | Huff, Barrington and Owens |