| Acronym | Definition |
|---|
| GCU | Grand Canyon University (Phoenix, Arizona, USA) |
| GCU | Glasgow Caledonian University |
| GCU | Glasgow Caledonian University (UK) |
| GCU | Groupement des Campeurs Universitaires (French camp association) |
| GCU | Grid Compute Utility |
| GCU | Government College University (Lahore, Pakistan) |
| GCU | Generator Control Unit |
| GCU | Greek Catholic Union |
| GCU | Ground Cooling Unit |
| GCU | General Contact Unit (fiction) |
| GCU | Gas Combustion Unit (nautical equipment installed on some LNG ships) |
| GCU | Guidance & Control Unit |
| GCU | Gun Control Unit |
| GCU | Génie Civil Urbain (French: Civil Urban Engineering) |
| GCU | Girl Crusaders' Union (UK) |
| GCU | Gateway Channel Unit |
| GCU | Ground Calibration Unit |