| Acronym | Definition |
|---|
| FOTB | Fall off the Bone (dining) |
| FOTB | Finger on the Button |
| FOTB | Flight of the Bumblebee (song) |
| FOTB | Frosting on the Beater (Posies album) |
| FOTB | Flash on the Beach (Flash Developers Conference, Brighton, UK) |
| FOTB | Friends of the Bridegroom |
| FOTB | Flash on the Beach (UK Conference; Adobe Flash) |
| FOTB | Fiber Optic Termination Box (various companies) |
| FOTB | Force of the Breaker (Yu-Gi-Oh trading card game set) |
| FOTB | Father of The Bride (movie) |
| FOTB | Fresh Off The Boat |
| FOTB | Fresh Out the Box |
| FOTB | Friends of The Bride (London indie band) |
| FOTB | Fecal Occult Blood Test |
| FOTB | Forum Of The Banned |
| FOTB | Fruit of the boom (Belgium dance party) |
| FOTB | Fall Of The Bastille (band) |
| FOTB | Flip Off The Board (polite form) |
| FOTB | First Off the Bench (basketball) |
| FOTB | Focus On The Basics |
| FOTB | Father of the Baby |