| Acronym | Definition |
|---|
| HDT | High Dose Therapy |
| HDT | Haus der Technik (German: The Art House) |
| HDT | Head-Down Tilt |
| HDT | Heat Deflection Temperature (plastics) |
| HDT | High Design Technology |
| HDT | Heavy Duty Truck |
| HDT | Heavy Duty Tire |
| HDT | Hard Disk Toolkit |
| HDT | Heatpipe Direct Touch (Xigmatek) |
| HDT | Heat Distortion Temperature (plastics) |
| HDT | Highest Dose Tested (EPA) |
| HDT | Henry David Thoreau |
| HDT | Heavy-Duty Truck |
| HDT | Hardware Detection Tool (software) |
| HDT | Host Digital Terminal |
| HDT | Hospitalisation à la Demande d'Un Tiers (French) |
| HDT | Holden Dealer Team |
| HDT | Header-Dictionary-Triples (resource description framework) |
| HDT | Help Desk Ticket (various organizations) |
| HDT | Hydrotreater (oil refinery) |
| HDT | Horse Driving Trials |
| HDT | High Definition Traffic (TomTom; Netherlands) |
| HDT | High Density Tape |
| HDT | Hawaiian Daylight Time |
| HDT | Hasse Diagram Technique |
| HDT | Huron Daily Tribune (Bad Axe, MI, USA) |
| HDT | Hardware Debug Tool (AMD) |
| HDT | High Resolution Dipmeter Tool (Schlumberger, borehole analysis) |
| HDT | Hazardous Devices Team |
| HDT | Helmet Drop Tower |
| HDT | Hybrid Discretionary Trust |
| HDT | Hot Dogger Tours (Brea, CA) |
| HDT | Handoff Detection Time |
| HDT | Hazardous Device Technician |
| HDT | Hosted Data Translation (Edict Systems) |
| HDT | Hospital Dying Trajectory |
| HDT | Harmonic Drive Technologies |
| HDT | Hemodialysis Treatment |
| HDT | Halo Dream Team (gaming) |
| HDT | Holiday Double Time (pay) |
| HDT | Hot Deck Temperature |
| HDT | Homeland Defense Training |