| Acronym | Definition |
|---|
| IGSS | Instituto Guatemalteco de Seguridad Social (Spanish: Guatemala Social Security Institute) |
| IGSS | Inspection Générale de la Sécurité Sociale (French: General Inspectorate of Social Security; Luxembourg) |
| IGSS | International Graduate School in Sociology (Bielefeld University; Bielefeld, Germany) |
| IGSS | International Graduate Summer School in Librarianship and. Information Science (Aberystwyth, Wales, UK) |
| IGSS | Integrated Global Studies School (New Trier Township High School; Illinois) |
| IGSS | Interactive Graphical SCADA System (Software) |
| IGSS | Interim Geographic Support System |
| IGSS | Illinois Ghost Seekers Society (Peoria, IL) |