| Acronym | Definition |
|---|
| IRSF | IOC (International Olympic Committee) Recognized Sports Federations |
| IRSF | International Rett Syndrome Foundation |
| IRSF | Inland Revenue Staff Federation (trade union; UK) |
| IRSF | International Rope Skipping Federation (Greenfield Park, QB, Canada) |
| IRSF | Indian Rope Skipping Federation |
| IRSF | International Revenue Share Fraud |
| IRSF | Interim Revenue Stabilisation Fund (now Heritage & Stabilisation Fund; Trinidad and Tobago) |
| IRSF | Initial Review Submission Form (Western Institutional Review Board; Olympia, WA) |