| Acronym | Definition |
|---|
| IRU | International Road Transport Union |
| IRU | Immune Recovery Uveitis (eyes) |
| IRU | Individual Rack Unit |
| IRU | Indefeasible Right of Use |
| IRU | Inertial Reference Unit |
| IRU | Indefeasible Rights of Use |
| IRU | Innovative Research Universities |
| IRU | Idaho Rivers United |
| IRU | Incident Response Unit (UK) |
| IRU | Instructional Resources Unit (various organizations) |
| IRU | Institutional Restructuring Unit (banking) |
| IRU | Indoor Receive Unit (satellite) |
| IRU | Irrevocable Reimbursement Undertaking (finance) |
| IRU | Inpatient Rehabilitation Unit (healthcare) |
| IRU | Individual Responsibility User |
| IRU | International Romany Union |
| IRU | International Relief Union |
| IRU | Internal Reference Unit |
| IRU | Integrated Recovery Utility |
| IRU | International Reform University |
| IRU | IVA Replacement Unit |
| IRU | Interface Receptacle Unit |
| IRU | Irrefutable Right of Usage |
| IRU | Infrared Receiver Unit |
| IRU | Integrated Recovery Unit |