| Acronym | Definition |
|---|
| ISAAC | International Symposium on Algorithms and Computation |
| ISAAC | International Society for Augmentative and Alternative Communication |
| ISAAC | International Symposium on Symbolic and Algebraic Computation |
| ISAAC | Information Sharing and Analysis Center (North Carolina) |
| ISAAC | International Symposium on Applied Corporate Computing |
| ISAAC | Indirection, Shift, Accumulate, Add and Count (cryptographic random number generator) |
| ISAAC | Interdistrict School for Arts and Communication |
| ISAAC | Internet System for Assessing Autistic Children |
| ISAAC | Integrated Synchronous and Asynchronous Collaboration |
| ISAAC | Integrated Security and Access Control (US FEMA) |
| ISAAC | International Study on Asthma and Allergy in Childhood |
| ISAAC | Information Selector and Automatic Copier |
| ISAAC | Integrated Systems And Automated Communications |
| ISAAC | Integrated Survivability Analysis and Assessment Code (trade-off tool) |