| Acronym | Definition |
|---|
| NESC | National Electrical Safety Code |
| NESC | National Environmental Services Center (West Virginia University) |
| NESC | National e-Science Centre (UK) |
| NESC | National Economic and Social Council (Ireland) |
| NESC | NASA Engineering and Safety Center |
| NESC | Non-English Speaking Country |
| NESC | National Exercise Simulation Center (US FEMA) |
| NESC | National Energy Skills Center (Trinidad and Tobago) |
| NESC | National Energy Software Center (obsolete; see ESTSC) |
| NESC | National Elite Sports Council (Australia) |
| NESC | National Environmental Satellite Center |
| NESC | Network for Evaluating Steel Components (United Kingdom) |
| NESC | Norwegian E-Sports Community (gaming forum) |
| NESC | Naval Electronics Systems Command (now SPAWAR) |
| NESC | New England Small Craft (Rowley, Massachusetts) |
| NESC | National Electrical Standards Committee |
| NESC | Nuclear and Environmental Safety Council |