| Acronym | Definition |
|---|
| ISSM | Ice Sheet System Model |
| ISSM | International Society for Sexual Medicine (Maarn, The Netherlands) |
| ISSM | Institut Steacie des Sciences Moléculaires (French: Steacie Institute for Molecular Sciences; Canada) |
| ISSM | Information Systems Security Manager |
| ISSM | International Symposium on Semiconductor Manufacturing |
| ISSM | Institute for the Study of Security Markets |
| ISSM | Institute of Sales and Marketing Management (UK) |
| ISSM | Interim Semi-Static Stability Model (DIME/PMESII tool for evaluating the situation in OOTW) |
| ISSM | Information Systems Security Monitoring |
| ISSM | Integrated Security Systems Management (Valencia, CA) |