| Acronym | Definition |
|---|
| ISSO | Information System Security Officer |
| ISSO | International Students and Scholars Office (college) |
| ISSO | Institute for Space Systems Operations |
| ISSO | Institute for Social and Sustainable Oikonomics (Germany) |
| ISSO | Information Systems Security Organization |
| ISSO | Information Systems Student Organization (various schools) |
| ISSO | International Side Saddle Organization (Stevensville, MD) |
| ISSO | Information Systems Security Office |
| ISSO | International Swaminarayan Satsang Organization |
| ISSO | Information Services Support Office (Army) |
| ISSO | International Self-Service Organization |