| Acronym | Definition |
|---|
| ISEC | Information Security (various organizations) |
| ISEC | Information Security |
| ISEC | International Society for Ecology and Culture |
| ISEC | Internal Security |
| ISEC | Instituto Superior de Engenharia de Coimbra (Portugal) |
| ISEC | International Superconductive Electronics Conference |
| ISEC | International Space Elevator Consortium (California) |
| ISEC | Inclusive and Supportive Education Congress (UK) |
| ISEC | International Society for Endangered Cats |
| ISEC | India Software Engineering Conference (est. 2008) |
| ISEC | International Special Education Congress |
| ISEC | US Army Information Systems Engineering Command |
| ISEC | Integrated Shipbuilding Environment Consortium |
| ISEC | International Symposium on Electromagnetic Compatibility |
| ISEC | International Science and Education Council |
| ISEC | International Stirling Engine Conference and Exhibition |
| ISEC | Interdisciplinary Studies in Early Childhood (academic program) |
| ISEC | Institute of Science Education and Culture (Kolkata, India) |
| ISEC | Intermountain Specialty Equipment Company |
| ISEC | Induction System Evaporative Cooling (aircraft engines) |