| Acronym | Definition |
|---|
| LRU | Least Recently Used |
| LRU | Line Replaceable Unit |
| LRU | Loi Relative aux Libertés et Responsabilités des Universités (French: Law on the Freedom and Responsibilities of Universities) |
| LRU | Line Replacement Unit |
| LRU | Lowest Replaceable Unit |
| LRU | Last Recently Used (less common) |
| LRU | Las Cruces, NM, USA (Airport Code) |
| LRU | Ley Orgánica de Reforma Universitaria (Spain) |
| LRU | Logical Remote Unit |
| LRU | Less-than-Release Unit |
| LRU | Life Raft Unit |
| LRU | Logistical Replacement Unit |
| LRU | Lethal RPG (Role Playing Game) Universe (game series) |