| Acronym | Definition |
|---|
| LGS | Light Green Seal (currency) |
| LGS | Local Gun Store |
| LGS | Loughborough Grammar School (UK) |
| LGS | Lane Guard System |
| LGS | Lennox-Gastaut Syndrome |
| LGS | Lead Generation Specialist (communications position) |
| LGS | Leaky Gut Syndrome |
| LGS | Langley Grammar School (UK) |
| LGS | Laser Guide Star |
| LGS | Lauriston Girls' School (Australia) |
| LGS | Light Gauge Steel (steel frame construction system) |
| LGS | Lodi Gas Storage (Houston, TX) |
| LGS | Langer-Giedion Syndrome |
| LGS | Louisiana Geological Society (est. 1934) |
| LGS | Law, Gender and Sexuality |
| LGS | Looking Glass Studios (game development company) |
| LGS | Local Game Store (roleplaying) |
| LGS | Low Growth Scenario (economic model) |
| LGS | Loan Guarantee Scheme (UK) |
| LGS | Light Gasoline Splitter (petroleum industry) |
| LGS | Large Group Speech (various organizations) |
| LGS | La Garde Suisse (French: Swiss Guard) |
| LGS | Low-Gravity Solids (oilfield) |
| LGS | Licensed Gun Store |
| LGS | Landsat-7 Ground Station |
| LGS | Legislation et Gestion Scolaire |
| LGS | Lets Get Serious |
| LGS | Louisiana Geriatrics Society |
| LGS | Layered Gene Scanning |
| LGS | Ladybird Grammar School (Karachi, Pakistan) |
| LGS | Location Grouping System |
| LGS | Location-Guided Steiner Tree |
| LGS | Lunar Geodetic Scout |
| LGS | Low-Grade Stockpile (mining) |