| Acronym | Definition |
|---|
| LSF | Linear Spectral Frequency (signal processing) |
| LSF | Langue des Signes Française (French Sign Language) |
| LSF | Lightweight Steel Framing |
| LSF | Lamp Survival Factor (lighting) |
| LSF | Load Sharing Facility |
| LSF | Lehre Studium Forschung (German: Teaching Education Research) |
| LSF | Lime Saturation Factor (raw materials) |
| LSF | Linux Socket Filter |
| LSF | Line Switch Frame |
| LSF | Library System File |
| LSF | Label Style File |
| LSF | Leased from |
| LSF | Line Spread Function |
| LSF | Lost Souls Forever |
| LSF | Learning for a Sustainable Future (est. 1991; Canada) |
| LSF | Les Savy Fav (band) |
| LSF | Low Smoke and Fume |
| LSF | Large-Scale Flow |
| LSF | Law Society Finals (UK) |
| LSF | Lanka Software Foundation (Sri Lanka) |
| LSF | Lyme sans Frontière (French: Lyme Disease without Border) |
| LSF | Luxembourg School of Finance (Luxembourg University) |
| LSF | Late SV40 Factor (mammalian transcription) |
| LSF | Liberty Security Force (gaming) |
| LSF | Linux Socket Filtering |
| LSF | Least Slack First |
| LSF | Libros sin Fronteras (Spanish: Books without Frontiers; Olympia, WA) |
| LSF | Lutheran Services of Florida |
| LSF | Light Strike Force (Singapore Police) |
| LSF | Laser-Saturated Fluorescence |
| LSF | Logistics Support Facility |
| LSF | Least Significant First (byte order) |
| LSF | Lost Strike Force (gaming clan) |
| LSF | Local Service Freeze |
| LSF | Linear State Feedback |
| LSF | Least Significant Figure |
| LSF | Longest Segment First |
| LSF | Life Sciences Facility |
| LSF | Lloyd Special Forces |
| LSF | Low-Stop Filter |
| LSF | Least Squares Fusion |
| LSF | Lesser Sciatic Foramen |
| LSF | Lower Support Frame |
| LSF | Line-Supervision Frame |
| LSF | Lone Star Football |