| Acronym | Definition |
|---|
| LSL | Lesotho Loti (ISO currency code) |
| LSL | Linden Scripting Language (scripting language Used Within Second Life) |
| LSL | Long Service Leave (Australia) |
| LSL | Leinster Senior League (Ireland) |
| LSL | Laminated Strand Lumber |
| LSL | Leisure Suit Larry |
| LSL | Logical Shift Left |
| LSL | Lower Specification Limit |
| LSL | Liquid Sound Lounge (est. 1993) |
| LSL | Link Support Layer |
| LSL | Load Segment Limit |
| LSL | Linux System Labs (Australia) |
| LSL | Lisa Scott-Lee (British pop star) |
| LSL | Linnean Society of London (UK) |
| LSL | Life Sciences Laboratory |
| LSL | Los Chiles, Costa Rica (airport code) |
| LSL | Lump Sum Leave |
| LSL | Least Squares Lattice |
| LSL | Landing Ship, Logistics |
| LSL | Locomotive Speed Limiter (used to stop a rail vehicle in an excessive overspeed condition) |
| LSL | Level Switch Low |
| LSL | Lower Statistical Limit |
| LSL | Logistics Support Library |
| LSL | Local Spherical Likelihood |
| LSL | Left Subscapular Line |