LOTO
| Acronym | Definition |
|---|---|
| LOTO | Leader of the Opposition |
| LOTO | Lake of the Ozarks (Missouri) |
| LOTO | Laughing on the Outside |
| LOTO | Lock Out Tag Out (safety) |
| LOTO | Landscape Opportunities for Territorial Organization (Italy) |
| LOTO | Lemmings of the Outback (online gaming community) |